Interpreting quantum nonlocality as platonic information

The "hidden variables" or "guiding equation" explanation for the measurement of quantum nonlocality (entanglement) effects can be interpreted as instantiation of Platonic information. Because these Bohm-deBroglie principles are already external to the material objects that they theoretically affect, interpreting them as Platonic is feasible. Taking an approach partially suggested by Quantum Information Theory which views quantum phenomena as sometimes observable-measurable information, this thesis defines hidden variables/guiding equation as information. This approach enables us to bridge the divide between the abstract Platonic realm and the physical world. The unobservable quantum wavefunction collapse is interpreted as Platonic instantiation. At each interaction, the wave function for a quantum system collapses. Instantly, Platonic information is instantiated in the system

Bounded-time fault-tolerant rule-based systems

Two systems concepts are introduced: bounded response-time and self-stabilization in the context of rule-based programs. These concepts are essential for the design of rule-based programs which must be highly fault tolerant and perform in a real time environment. The mechanical analysis of programs for these two properties is discussed. The techniques are used to analyze a NASA application

Mineralogy and chemistry of the Hagerstown soil in Missouri

Material in this bulletin is largely taken from the Ph. D. thesis by J.E. Brydon 'A study of the Mineralogy of the Hagerstown Silt Loam in Missouri,' University of Missouri, June, 1956--P. [2].Digitized 2007 AES.Includes bibliographical references (pages 53-56)

Mineralogical study of Lindley soil in Missouri

The experimental material is taken from the M.S. thesis of J.E. Brydon... the study forms part of the Department of Soils Research Project 6, 'Heavy Clays'--P. [3].Digitized 2007 AES.Includes bibliographical references (pages 36-38)

The Large and Small Scale Structures of Dust in the Star-Forming Perseus Molecular Cloud

We present an analysis of ~3.5 square degrees of submillimetre continuum and extinction data of the Perseus molecular cloud. We identify 58 clumps in the submillimetre map and we identify 39 structures (`cores') and 11 associations of structures (`super cores') in the extinction map. The cumulative mass distributions of the submillimetre clumps and extinction cores have steep slopes (alpha ~ 2 and 1.5 - 2 respectively), steeper than the Salpeter IMF (alpha = 1.35), while the distribution of extinction super cores has a shallow slope (alpha ~ 1). Most of the submillimetre clumps are well fit by stable Bonnor-Ebert spheres with 10K < T < 19K and 5.5 < log_10(P_ext/k) < 6.0. The clumps are found only in the highest column density regions (A_V > 5 - 7 mag), although Bonnor-Ebert models suggest that we should have been able to detect them at lower column densities if they exist. These observations provide a stronger case for an extinction threshold than that found in analysis of less sensitive observations of the Ophiuchus molecular cloud. The relationship between submillimetre clumps and their parent extinction core has been analyzed. The submillimetre clumps tend to lie offset from the larger extinction peaks, suggesting the clumps formed via an external triggering event, consistent with previous observations.Comment: 38 pages, 12 figures, accepted by Astrophysical Journal slight changes to original due to a slight 3" error in the coordinates of the SCUBA ma

Baleen whales host a unique gut microbiome with similarities to both carnivores and herbivores

Mammals host gut microbiomes of immense physiological consequence, but the determinants of diversity in these communities remain poorly understood. Diet appears to be the dominant factor, but host phylogeny also seems to be an important, if unpredictable, correlate. Here we show that baleen whales, which prey on animals (fish and crustaceans), harbor unique gut microbiomes with surprising parallels in functional capacity and higher level taxonomy to those of terrestrial herbivores. These similarities likely reflect a shared role for fermentative metabolisms despite a shift in primary carbon sources from plant-derived to animal-derived polysaccharides, such as chitin. In contrast, protein catabolism and essential amino acid synthesis pathways in baleen whale microbiomes more closely resemble those of terrestrial carnivores. Our results demonstrate that functional attributes of the microbiome can vary independently even given an animal-derived diet, illustrating how diet and evolutionary history combine to shape microbial diversity in the mammalian gut

ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase

Metastatic colonization involves paracrine/juxtacrine interactions with the microenvironment inducing an adaptive response through transcriptional regulation. However, the identities of transcription factors (TFs) induced by the metastatic microenvironment in ovarian cancer (OC) and their mechanism of action is poorly understood. Using an organotypic 3D culture model recapitulating the early events of metastasis, we identified ETS1 as the most upregulated member of the ETS family of TFs in metastasizing OC cells as they interacted with the microenvironment. ETS1 was regulated by p44/42 MAP kinase signaling activated in the OC cells interacting with mesothelial cells at the metastatic site. Human OC tumors had increased expression of ETS1, which predicted poor prognosis. ETS1 regulated OC metastasis both in vitro and in mouse xenografts. A combination of ChIP-seq and RNA-seq analysis and functional rescue experiments revealed FAK as the key transcriptional target and downstream effector of ETS1. Taken together, our results indicate that ETS1 is an essential transcription factor induced in OC cells by the microenvironment, which promotes metastatic colonization though the transcriptional upregulation of its target FAK